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PE anti-human CXCR7 Antibody

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Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Product Citations
  1. Doijen J, et al. 2017. PLoS One. 10.1371/journal.pone.0185354. PubMed
RRID
AB_2565680 (BioLegend Cat. No. 391403) AB_2565681 (BioLegend Cat. No. 391404)

Antigen Details

Structure
G Protein-Coupled Receptor super family
Distribution
Monocytes, B cells, T cells, and mature dendritic cells.
Function
Regulates trafficking and activation of leukocytes.
Ligand/Receptor
CXCL12/SDF-1 and CXCL11/I-TAC.
Cell Type
Monocytes, B cells, T cells, Dendritic cells
Biology Area
Cell Biology, Immunology, Signal Transduction
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Torossian F, et al. 2014. Blood 123:191.
2. Walentowicz-Sadlecka M, et al. 2014. PLoS One 1:e84629.
3. Yates TJ, et al. 2013. Cancer 119:61.
4. Burns JM, et al. 2006. J. Exp. Med. 203:2201.
5. Infantino S, et al. 2006. J. Immunol. 176:2197.

Gene ID
57007 View all products for this Gene ID
UniProt
View information about CXCR7 on UniProt.org
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