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Product Details
- Verified Reactivity
- Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant rat NKG2A-Fc fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Sasther PC, et al, 2011, J Immunol, 187:6365
- RRID
- AB_2716215 (BioLegend Cat. No. 250702)
Antigen Details
- Structure
- Type II transmembrane protein
- Distribution
-
NK cells, a subset of CD8+ T-lymphocytes.
- Function
- Signal transduction, Receptor for non-classical MHC Class I molecules
- Interaction
- DAP10, DAP12, CD94
- Ligand/Receptor
- Non-classical MHC Class I glycoproteins
- Cell Type
- NK cells, T cells
- Biology Area
- Immunology
- Molecular Family
- MHC Antigens
- Antigen References
-
- Berg SF, et al. 1998. Eur J Immunol, 28:444.
- Vance RE, et al. 1999. J Exp Med. 190(12).
- Vance RE, et al. 1998. J Exp Med. 188(10).
- Flornes LM, et al. 2010, Immunogenetics, 62:521
- Dissen E, et al. 2008. Semin Immunol. 20:369
- Gene ID
- 500338 View all products for this Gene ID 29683 View all products for this Gene ID 29684 View all products for this Gene ID
- UniProt
- View information about NKG2A/C/E on UniProt.org
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