中胚层配对同源蛋白2抗体

英文名称：英文名称PRRX2
产品类别：抗体
产品编号：YS19434
产品应用： ELISA IHC-P IHC-F ICC IF
保质期：12个月
保存条件：-20

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50ul

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英文名称	PRRX2
中文名称	中胚层配对同源蛋白2抗体
别名	Paired mesoderm homeobox protein 2; Paired related homeobox protein 2; paired-like homeobox gene 2; paired-like homeodomain protein PRX2; Paired-related homeobox protein 2; PMX2; Predicted NUP98/PRRX2 fusion protein; Prrx2; PRRX2_HUMAN; PRX 2; PRX-2; PRX2.
研究领域	细胞生物免疫学发育生物学转录调节因子表观遗传学
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, )
产品应用	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
理论分子量	27kDa
细胞定位	细胞核
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human PRRX2: 131-230/253
亚型	IgG
纯化方法	affinity purified by Protein A
缓冲液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
产品介绍	The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq, Jul 2008] Function: May play a role in the scarless healing of cutaneous wounds during the first two trimesters of development. Subcellular Location: Nucleus. Tissue Specificity: In fetal skin, highest expression found in cells of mesodermal origin within the dermal papilla of the developing hair shaft. Not detected in epidermis or dermis. In adult skin, weakly expressed within the basal layers of the epidermis. Not expressed in dermis. Similarity: Belongs to the paired homeobox family. Contains 1 homeobox DNA-binding domain.