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辣根过氧化物酶标记的兔抗大鼠IgM

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产品编号bs-0346R-HRP
英文名称Rabbit Anti-Rat IgM / HRP antibody
中文名称辣根过氧化物酶标记的兔抗大鼠IgM
别    名Rabbit Anti-Rat IgM (HRP); Immunoglobulin M;   
Specific References  (3)     |     bs-0346R-HRP has been referenced in 3 publications.
[IF=5.116] Chunyu Jiang. et al. Upregulating CXCR7 accelerates endothelial progenitor cell-mediated endothelial repair by activating Akt/Keap-1/Nrf2 signaling in diabetes mellitus. Stem Cell Res Ther. 2021 Dec;12(1):1-15  WB ;  Rat.  
[IF=2.784] Guo X et al.RP105 ameliorates hypoxia?reoxygenation injury in cardiac microvascular endothelial cells by suppressing TLR4?MAPKs?NF-κB signaling.Int J Mol Med. 2018 Jul;42(1):505-513.  WB ;  Rat.  
[IF=0.46] Su, Yuqing, et al. "Mixed PEGylated surfactant modifying system decrease the accelerated blood clearance phenomenon of nanoemulsions in rats."Asian Journal of Pharmaceutical Sciences (2016).  ELISA ;  Rat.  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Rat
产品应用WB=1:1000-10000, IHC-P=1:100-500, IHC-F=1:100-1000, ELISA=1:1000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性    状Liquid
浓    度2.0 mg/ml
免 疫 原Native Rat IgM 
亚    型IgG
纯化方法affinity purified by Protein A
缓 冲 液10 mM TBS (pH=7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol.
保存条件Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.

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