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| 产品编号 | bs-42309P |
| 英文名称 | Recombinant human IL-18 protein |
| 中文名称 | 重组人IL18蛋白 |
| 别 名 | Interleukin-18; interferon gamma-inducing factor IGIF; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; Iboctadekin; IFN gamma inducing factor; IGIF; IL 1 gamma; IL 18; IL-18; IL 1g; IL1 gamma; IL18 protein; IL1F4; IL1g; IL1gamma; ILIF4; Interferon gamma inducing factor; Interleukin 1 gamma; Interleukin18; MGC12320; IL18_HUMAN |
| 理论分子量 | 18.2kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | >1mg/ml |
| 物 种 | Human |
| 序 列 | 37-193/193 |
| 纯 度 | >90% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | E.coli |
| 标签 | Tag Free |
| 缓 冲 液 | 20mM Tris-Hcl (pH=8.0) with 2M Urea |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. SWISS: P97636 Gene ID: 29197 IL-18是巨噬细胞分泌的一个重要因子,它具有多种免疫功能,能诱导产生IFNγ,无论在病毒感染早期或特异性细胞免疫应答效应阶段都会出现,因此IL-18主要参与免疫应答及炎性细胞浸润的改变。Interleukin-18 又称inteferon-gamma inducing factor(IGIF),在辅助T细胞的应答反应中起重要作用。IL-18和IL-1一起,既参与先天免疫,又是后天免疫的构成因素。 |
| 产品图片 | |
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