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重组人IL18蛋白

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产品编号bs-42309P
英文名称Recombinant human IL-18 protein
中文名称重组人IL18蛋白
别    名Interleukin-18; interferon gamma-inducing factor IGIF; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; Iboctadekin; IFN gamma inducing factor; IGIF; IL 1 gamma; IL 18; IL-18; IL 1g; IL1 gamma; IL18 protein; IL1F4; IL1g; IL1gamma; ILIF4; Interferon gamma inducing factor; Interleukin 1 gamma; Interleukin18; MGC12320; IL18_HUMAN  
理论分子量18.2kDa
性    状Lyophilized or Liquid
浓    度>1mg/ml
物    种Human
序    列37-193/193
纯    度>90% as determined by SDS-PAGE
纯化方法AC
内毒素Not analyzed
表达系统E.coli
标签Tag Free
缓 冲 液20mM Tris-Hcl (pH=8.0) with 2M Urea
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.

SWISS:
P97636

Gene ID:
29197

IL-18是巨噬细胞分泌的一个重要因子,它具有多种免疫功能,能诱导产生IFNγ,无论在病毒感染早期或特异性细胞免疫应答效应阶段都会出现,因此IL-18主要参与免疫应答及炎性细胞浸润的改变。Interleukin-18 又称inteferon-gamma inducing factor(IGIF),在辅助T细胞的应答反应中起重要作用。IL-18和IL-1一起,既参与先天免疫,又是后天免疫的构成因素。
产品图片
The purity of the protein is greater than 80% as determined by reducing SDS-PAGE.
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