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重组小鼠CD80蛋白

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产品编号bs-43640P
英文名称Recombinant mouse CD80 protein, C-His (HEK293)
中文名称重组小鼠CD80蛋白
别    名Activation B7-1 antigen; B lymphocyte activation antigen B7; B7; B7-1; B7-1 antigen; BB1; CD28 antigen ligand 1; CD28LG; CD28LG1; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 antigen; CD80 molecule; CD80_HUMAN; Costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; T-lymphocyte activation antigen CD80; CD80_MOUSE.  
理论分子量25.8kDa
性    状Lyophilized or Liquid
浓    度>0.5mg/ml
物    种Mouse
序    列37-245/306
纯    度>90% as determined by SDS-PAGE
纯化方法AC
内毒素Not analyzed
表达系统HEK293 cell
标签C-His
缓 冲 液PBS (pH=7.4)
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines.

SWISS:
P33681

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The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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