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重组人抗利尿激素/血管升压素/加压素/血管加压素蛋白

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产品编号bs-43179P
英文名称Recombinant human Vasopressin-neurophysin 2-copeptin protein, C-His (HEK293)
中文名称重组人抗利尿激素/血管升压素/加压素/血管加压素蛋白
别    名Vasopressin; Antidiuretic Hormone; Arginine Vasopressin; ADH; Arginine vasopressin neurophysin II; ARVP; AVP; AVP NPII; AVRP; Vasopressin neurophysin 2 copeptin precursor; Vasopressin neurophysin II copeptin; NEU2_HUMAN; VP.  
理论分子量17.4kDa
性    状Lyophilized or Liquid
浓    度>0.5mg/ml
物    种Human
序    列20-164/164
纯    度>90% as determined by SDS-PAGE
纯化方法AC
内毒素Not analyzed
表达系统HEK293 cell
标签C-His
缓 冲 液PBS (pH=7.4)
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍Vasopressin, also known as arginine vasopressin (AVP) or antidiuretic hormone (ADH), is a posterior pituitary hormone that is synthesised in the hypothalamus. Vasopressin is synthesised as a precursor protein that consists of arginine vasopressin and two associated proteins, neurophysin 2 and the glycopeptide copeptin. Vasopressin, together with its carrier protein neurophysin II, is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. Vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney and also causes vasoconstriction of the peripheral vessels. Vasopressin can also contract smooth muscle during parturition and lactation. It also plays a role in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in the vasopressin precursor cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI), which is characterised by persistant thirst, polydipsia and polyuria.

SWISS:
P01185

Gene ID:
551

Copeptin是NEU2_HUMAN 的一段活性多肽,区间126-164/164aa
产品图片
The purity of the protein is greater than 85% as determined by reducing SDS-PAGE.
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