您好,欢迎光临上海雅吉生物商城!
工作时间:9:00-18:00
全国服务热线:021-34661276

重组人补体C1Q蛋白

规格
价格库存
订购热线:021-34661276
我要询价
  • 商品详情
  • 售后服务
  • 相关文献

产品编号bs-43200P
英文名称Recombinant human C1Q protein, C-His (HEK293)
中文名称重组人补体C1Q蛋白
别    名Complement C1q subcomponent subunit A; Complement C1q subcomponent subunit B; Complement C1q subcomponent subunit C; C1QA_HUMAN; C1QB_HUMAN; C1QC_HUMAN;  
理论分子量48.4kDa
性    状Lyophilized or Liquid
浓    度>0.5mg/ml
物    种Human
纯    度>90% as determined by SDS-PAGE
纯化方法AC
内毒素Not analyzed
表达系统HEK293 cell
标签C-His
缓 冲 液PBS (pH=7.4)
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍C1q, a subcomponent of the classical complement pathway, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B, while three of these subunits, designated C1q-A through C1q-C, are disulfide-linked dimers of chain C. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. However, its ability to modulate the interaction of platelets with collagen and immune complexes suggests C1q influences homeostasis as well as other immune activities, and perhaps thrombotic complications resulting from immune injury. Defects in C1q-A, C1q-B and C1q-C cause inactivation of the classical pathway, leading to a rare genetic disorder characterized by lupus-like symptoms.

SWISS:
P02747

Gene ID:
712

产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
我要询价
*联系方式:
(可以是QQ、MSN、电子邮箱、电话等,您的联系方式不会被公开)
*内容:


微信客服
扫一扫立即咨询


微信客服
扫一扫立即咨询

销售电话:

021-34661275

021-34661276

15301693058