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| 产品编号 | bs-42334P |
| 英文名称 | Recombinant human VIPR2 protein, N-Trx-His |
| 中文名称 | 重组人腺苷酸环化酶激活肽受体-II蛋白 |
| 别 名 | VIP receptor II; VIP receptor2; VIP receptor-2; PACAP type-3; VIP type-2 receptor; Vip2; VPAC2; VPAC2R; Vasoactive intestinal polypeptide receptor 2; VIP-R-2; Pituitary adenylate cyclase-activating polypeptide type III receptor; PACAP type III receptor; PACAP-R-3; PACAP-R3; VIPR2_HUMAN. |
| 理论分子量 | 29.1kDa |
| 性 状 | Liquid |
| 浓 度 | >0.5mg/ml |
| 物 种 | Human |
| 序 列 | 24-121/438 |
| 纯 度 | >90% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | E.coli |
| 标签 | N-Trx-His |
| 缓 冲 液 | 20mM Tris-Hcl (pH=8.0) |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide belonging to the vasoactive intestinal polypeptide/glucagon/ secretin family. It is widely distributed in the body, and a variety of biological actions have been reported. Recent studies have shown that there is a family of PACAP receptors (PACAPRs), and two members of this family have been identified. Mouse PACAPR-3 is a protein of 437 amino acids that has 50% and 51% identity with rat PACAP type I and type II receptors, respectively. It binds to vasoactive intestinal polypeptide as well as PACAP-38 and -27, with a slightly higher affinity for PACAP-38, PACAPR-3 mRNA is expressed at high levels in MIN6, at moderate levels in pancreatic islets and other insulin-secreting cell lines, HIT-T15 and RINm5F, as well as in the lung, brain, stomach, and colon, and at low levels in the heart. PACAPR-3 participates in the regulation of insulin secretion. insulin secretion from MIN6 cells is significantly stimulated by PACAP-38. SWISS: P35000 Gene ID: 7434 PACAP 受体分为两个亚型，PACAP-2型受体对PACAP是特异性的，与PACAP的亲和力比VIP高100-1000倍，PACAP-II型受体与PACAP和VIP的亲和力相似，对二者无选择性。此抗体即为后者。 |
| 产品图片 |  The purity of the protein is greater than 80% as determined by reducing SDS-PAGE. |
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