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重组人ras癌基因家族Rab11蛋白

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产品编号bs-42325P
英文名称Recombinant human Rab11 protein, N-His
中文名称重组人ras癌基因家族Rab11蛋白
别    名MGC1490; Rab 11; Rab 11A; RAB 11A member oncogene family; RAB 11A, member oncogene family; Rab-11; RAB11 A; RAB11; RAB11A; RAB11A member RAS oncogene family; Ras related protein Rab 11A; Ras related protein Rab11A; Ras-related protein Rab-11A; RB11A_HUMAN; YL 8; YL8.  
理论分子量27.8kDa
性    状Liquid
浓    度>0.5mg/ml
物    种Human
序    列2-213/216
纯    度>90% as determined by SDS-PAGE
纯化方法AC
内毒素Not analyzed
表达系统E.coli
标签N-His
缓 冲 液20mM Tris-Hcl (pH=8.0)
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There are over 40 Rab proteins in mammals. Rab11a and Rab11b are known markers for protein trafficking, sorting, and recycling in the endosomal pathway. The Rab11 proteins are enriched in recycling endosomes and the trans-Golgi network, where they regulate membrane recycling back to the plasma membrane. Rab11a is ubiquitously expressed, while Rab11b is expressed mainly in the heart and brain.

SWISS:
P62491

Gene ID:
8766

产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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