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重组人E选择素蛋白

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产品编号bs-43646P
英文名称Recombinant human E-Selectin protein, C-His (HEK293)
中文名称重组人E选择素蛋白
理论分子量60.6kDa
性    状Lyophilized or Liquid
浓    度>1mg/ml
物    种Human
序    列22-556/610
纯    度>90% as determined by SDS-PAGE
纯化方法AC
内毒素Not analyzed
表达系统HEK293 cell
标签C-His
缓 冲 液PBS (pH=7.4)
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008]

SWISS:
P16581

Gene ID:
6401

E选择素(CD62E)是活化的内皮细胞表面表达的黏附分子,是白细胞与内皮细胞形成接触时的启动因子。E选择素是表达在血管内皮细胞表面的黏附分子。
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The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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