重组人 FCGRT & B2M Heterodimer 蛋白

规格

价格库存

订购热线：021-34661276

产品编号	bs-43201P
英文名称	Recombinant human FCGRT&B2M Heterodimer protein, C-His (HEK293)
中文名称	重组人 FCGRT & B2M Heterodimer 蛋白
理论分子量	31.8&11.7kDa
性　　　　状	Lyophilized or Liquid
浓　　　　度	>1mg/ml
物　　　　种	Human
纯　　　　度	>90% as determined by SDS-PAGE
纯化方法	AC
内毒素	Not analyzed
表达系统	HEK293 cell
标签	C-His
保存条件	Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍	FcRN present in the intestinal epithelium of neonatal mice and rats mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn animals to acquire passive immunity. FcRn (also designated FCGRT, Brambell receptor, FcRn ? chain, IgG Gc receptor and neonatal Fc-receptor) is comprised of a heavy chain and ∫-2-Microglobulin. FcRn heavy chain shows approximately 35% amino acid identity to an MHC class I molecule. FcRN localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal catabolism. This protection mechanism is a major constituent for ensuring IgG are the longest lived of all plasma proteins. SWISS: P55899 Gene ID: 2217
产品图片	The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.