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| 产品编号 | V6701 |
| 英文名称 | TSH |
| 中文名称 | 人促甲状腺激素β亚基单克隆抗体 |
| 别 名 | TSHB_HUMAN; Thyrotropin subunit beta; Thyroid-stimulating hormone subunit beta (TSH-B; TSH-beta); Thyrotropin beta chain; Thyrotropin alfa; TSH-β; |
| 克 隆 号 | 7H1 |
| 理论分子量 | 12kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 缓 冲 液 | 0.01M PBS(pH7.4) |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013] Function: Indispensable for the control of thyroid structure and metabolism. Subunit: Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. Subcellular Location: Secreted. Similarity: Belongs to the glycoprotein hormones subunit beta family. SWISS: P01222 Gene ID: 7252 Database links: Entrez Gene: 7252 Human SwissProt: P01222 Human TSHB（甲状腺刺激激素亚基Beta）是一种蛋白质编码基因。 与TSHB相关的疾病包括甲状腺功能减退，先天性，非甲状腺功能减退4和中枢性先天性甲状腺功能减退。其相关途径包括通过GPCR进行信号传递和肽激素代谢。与该基因相关的基因本体论（GO）注释包括激素活性。该基因的重要旁系同源物是FSHB。 |
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